Exposure to hazardous chemotherapy drugs increases risk of chromosomal damage, adverse reproductive outcomes and cancers1 for healthcare workers.

With HALYARD*, you can provide staff with personal protective equipment exceeds all industry testing standards to ensure their safety.

The risk of handling chemotherapy drugs is extremely high. Is your staff properly protected?

There is no safe level of exposure for healthcare workers. In one study, 17% of nurses experienced unintentional skin and eye exposure to chemotherapy agents2.

According to a study conducted by NIOSH, many respondents reported not even wearing gloves and gowns when administering chemotherapy – the minimum PPE requirements.3

According to a study conducted by NIOSH, use of PPE was improved when:

  • Workers were more familiar with safe handling guidelines
  • Specific safe handling procedures were present
  • Perceived management commitment to safety was higher3


Number of chemotherapy drugs HALYARD* chemo gowns and gloves are tested against

Compared to 10 or fewer for most gowns and gloves⁴

Keep your healthcare workers safe with HALYARD* CHEMO GEAR* and our supportive guides and content

We want to make sure your staff has the right personal protective equipment and knows how to wear it, for personal safety and compliance with USP <800>.

Halyard offers chemo gloves, chemo gowns, N95 respirator masks, and full chemo kits to keep your clinicians safe, whether administering, compounding or transporting chemotherapy drugs.

PURPLE NITRILE-XTRA* Gloves, PINK UNDERGUARD* Gloves and CHEMO360* Gowns for Chemotherapy Use have been tested for resistance to 52 chemotherapy drugs.

Arsenic Trioxide (1 mg/ml)

Azacitidine (Vidaza) (25 mg/ml)

Bendamustine (5 mg/ml)

Bleomycin Sulfate (15 mg/ml)

Bortezomib (Velcade) (1 mg/ml)

Busulfan (6 mg/ml)

Carboplatin (10 mg/ml)

Carfilzomib (2 mg/ml)

Carmustine (3.3 mg/ml)

Cetuximab (Erbitux) (2 mg/ml)

Cisplatin (1 mg/ml)

Cyclophosphamide (20 mg/ml)

Cytarabine HCl (100 mg/ml)

Cytovene (10 mg/ml)

Dacarbazine (10 mg/ml)

Daunorubicin HCl (5 mg/ml)

Decitabine (5 mg/ml)

Docetaxel (10 mg/ml)

Doxorubicin HCl (2 mg/ml)

Eribulin Mesylate (0.5 mg/ml)

Etoposide (20 mg/ml)

Fludarabine (25 mg/ml)

Fluorouracil (50 mg/ml)

Fulvestrant (50 mg/ml)

Gemcitabine (38 mg/ml)

Idarubicin (1 mg/ml)

Ifosfamide (50 mg/ml)

Irinotecan (20 mg/ml)

Mechlorethamine HCl (1 mg/ml)

Melphalan (5 mg/ml)

Methotrexate (25 mg/ml)

Mitomycin (0.5 mg/ml)

Mitoxantrone (2 mg/ml)

Oxaliplatin (2 mg/ml)

Paclitaxel (6 mg/ml)

Paraplatin (10 mg/ml)

Pemetrexed (25 mg/ml)

Pertuzumab (30 mg/ml)

Raltitrexed (0.5 mg/ml)

Retrovir (10 mg/ml)

Rituximab (10 mg/ml)

Temsirolimus (25 mg/ml)

Trastuzumab (21 mg/ml)

ThioTEPA (10 mg/ml)

Topotecan HCl (1 mg/ml)

Triclosan (1 mg/ml)

Vincrinstine Sulfate (1 mg/ml)

Vinblastine (1 mg/ml)

Vinorelbine (10 mg/ml)

Zoledronic Acid (0.8 mg/ml)

Testing measured no breakthrough at the Standard Breakthrough Rate of 0.1ug/cm2/minute, up to 240 minutes for gloves and 480 minutes for gowns, except for carmustine. Camustine breakthrough occurred at 80.4 minutes on gloves and 33.3 minutes on gowns.

Wear the battle gear that protects against 52 chemotherapy drugs
See the line of HALYARD* Chemo Gear that can protect your healthcare workers and adheres to stricter USP <800> guidelines

Following USP <800> standards for use of PPE

The new USP <800> standard provides guidance for PPE selection based on whether wearers are administering, compounding, or transporting hazardous drugs.

Things to know about protecting staff from chemotherapy drugs


Any drug used in cancer treatment (except those in solid oral dosage forms that require only counting or packaging) listed in National Institute for Occupational Safety and Health’s (NIOSH) group 1 requires full compliance with the USP standards.5


There are specific directions for donning, doffing and disposing of PPE used in the administration of chemotherapy. Ensure staff follows these protocols. This article can help.


Check that guidelines are followed for each category of chemo PPE. Download this helpful guide.

Halyard offers some of the most extensively chemo-tested gloves and gowns available – far more than indicated for most competitive gowns and gloves.

Gear up for the fight now because there is no safe level of exposure to cytotoxic chemotherapy drugs for healthcare workers. New, stricter guidelines on hazardous drugs handling in a healthcare setting – USP <800> – applies to all healthcare personnel with no exceptions.

Guide to the USP <800> guidelines for PPE use when administering chemotherapy drugs
There is no safe level of exposure to cytotoxic chemotherapy drugs for healthcare workers. Follow these latest guidelines for PPE to reduce risk.
Guide to the USP <800> guidelines for PPE use when compounding chemotherapy drugs
For those compounding and packaging chemotherapy drugs, the PPE requirements in USP<800> are rigorous, because there are so many opportunities for exposure.

HALYARD* CHEMO360* Procedure Gown Tested For Use With Chemotherapy Drugs

HALYARD* Procedure Gowns for Use with Chemotherapy Drugs meet OSHA, ASHP and ONS recommendations, as well as ASTM liquid barrier standards F1670 and F1671.


  • Tested against 52 chemotherapy drugs on fabric and seams
  • Meets USP <800> Guidelines and passed ASTM F739-12
  • Fabric chemo-rated. Passed ASTM F1670 & F1671.

  • Closed in the back, with a secure tape closure, to provide more protection from exposure
  • Knit cuffs>
  • Ultra Sonic seam closure

HALYARD* CHEMO360* Procedure Gown
Choose HALYARD* CHEMO360* Chemotherapy Procedure Gown to protect yourself against 52 chemotherapy drugs!
PURPLE NITRILE-XTRA* Exam Gloves offer the highest level of chemotherapy protection available in HALYARD’S line of nitrile exam gloves.


PURPLE NITRILE-XTRA* Exam Gloves are an excellent choice for protection against chemical exposure. They have been tested against 52 chemotherapy drugs per the ASTM D6978, Standard Practice for Assessment of Resistance of Medical Gloves to Permeation by Chemotherapy Drugs, as well as common chemicals found in the healthcare environment.


  • Meets or exceeds ASTM D6319 – Standard Specification for Nitrile Examination Glove for Medical Applications
  • Meets or exceeds biocompatible 10993 studies for systemic toxicity, irritation and sensitization endpoints
  • Passes Viral Penetration Testing – ASTM F1671 – 07 Standard Test Method for Resistance of Materials Used in Protective Clothing to Penetration by Blood-Borne Pathogens Using Phi-X174 Bacteriophage Penetration as a Test System

  • Gloves should be worn for all activities involving chemotherapy drugs, including compounding, administration, handling of waste from recently treated patients, and cleanup of spills.
  • Select disposable, chemotherapy qualified, powder-free gloves that extend over the gown cuffs.6, 7, 8, 9
  • If double-gloving, one pair should be worn under the gown cuff and the other worn over the gown cuff.
  • If single-gloving, the gloves should be worn over the gown cuff.

PINK UNDERGUARD* Nitrile Exam Gloves

As new PPE protocols for handling chemotherapy agents are implemented, it is imperative to have a chemotherapy glove that appropriately protects healthcare professionals and makes compliance to double gloving easy. PINK UNDERGUARD* does both!


  • Using PINK UNDERGUARD* as an under glove reduces double gloving time by up to 52.7% compared to double gloving the top two leading competitive extended cuff chemotherapy gloves.
  • PINK UNDERGUARD* and PURPLE NITRILE-XTRA* double gloving solution exhibits reduced donning time by up to 44.4% compared to double gloving the top two leading competitive extended cuff chemotherapy gloves.
  • PINK UNDERGUARD* and PURPLE NITRILE-XTRA* double gloving solution received a 100% acceptance rate for ease of donning versus 44% and 26% on the top two leading competitive extended cuff chemotherapy glove combinations.

  • Cleared for Use with Chemotherapy Drugs
  • For use with low to high expected exposure to fluids or chemicals
  • Meets or exceeds Acceptable Quality Level (AQL)
  • Meets or exceeds ASTM D5151 Test Standards
  • Meets or exceeds ASTM D6319 Test Standards
  • Meets or exceeds Biocompatibility-ISO Standard for Primary Skin Irritation & Sensitivity

PINK UNDERGUARD* Nitrile Exam Gloves
First medical exam glove specifically designed to help healthcare professionals comply with recommended double gloving protocols when handling chemotherapy drugs.

Proper donning and doffing techniques are critical for safety. Use this video for helpful staff support in adhering to protocol.

Recent articles & resources

5 things to know about protecting yourself from chemotherapy drugs
Guide to Compounding
4 Things You Can do Right Now to Get Ready for USP <800>

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  1. Polovich M. Chemotherapy Safe Handling: What You Need to Know. 2015.
  2. Friese, CR, Himes-Ferris, L, Frasier, MN. Structures and processes of care in ambulatory oncology settings and nurse-reported exposure to chemotherapy. BMJ Quality and Safety. 2011
  3. CDC Web Site:
  4. Halyard* Purple Nitrile-Xtra* Exam Gloves and Halyard* Procedure Gowns Tested for Use with Chemotherapy
  5. Kienle et al, The Chapter <800> Answer Book, ASHP Publications, Kienle, Patricia C, , 2017, p vii.

Based on 2018 extended cuff chemotherapy gloves sales data

  1. Oncology Nursing Society (ONS): Chemotherapy and Biotherapy Guidelines and Recommendations for Practice 2005.
  2. American Society of Health-System Pharmacists (ASHP): Guidelines on Handling Hazardous Drugs. Am J.Health-Syst Pharm 2006; 63:1172-9
  3. Occupational Safety and Administration (OSHA): Controlling Occupational Exposure to Hazardous Drugs.
  4. National Institute for Occupational Safety and Health (NIOSH): Preventing Occupational Exposure to Antineoplastic and Other Hazardous Drugs in Health Care Settings, September 2004-165. OSHA recommends changing gloves every hour when working with cytotoxic drugs.